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  • 5-HT1A receptor - Wikipedia, the free encyclopedia
    The 5-HT1A receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). It is a G protein-coupled receptor (GPCR) that is coupled to Gi/Go and mediates inhibitory ...
    http://en.wikipedia.org/wiki/5-HT1A_receptor
  • In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A - NCBI
    In the dorsal raphe nucleus (DR), extracellular serotonin (5-HT) regulates serotonergic transmission through 5-HT1A ... The selective 5-HT1B receptor agonist 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrolo[3,2-b]pyridin-5- one ...
    http://www.ncbi.nlm.nih.gov/pubmed/15009637
  • Intracellular Loop 2 Peptides of the Human 5HT1a Receptor are ...
    Peptide mimics of intracellular loop 2 (ic2) of the human 5HT1a receptor have been studied with respect to their ability to ... the transmembrane 5-intracellular loop 3 region of the human 5H T 1A receptor,” Biochemistry and Cell Biology, vol.
    http://www.hindawi.com/journals/ijpep/2012/490734/
  • The Role of 5-HT1A/B Autoreceptors in the Antinociceptive Ef ...
    The Role of 5-HT1A/B Autoreceptors in the Antinociceptive Effect of Systemic Administration of Acetaminophen .... (8-OH-DPAT; Sigma), and 1,4-Dihydro-3-(1, 2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrolo[3,2-b]pyridin-5-one (CP 93129; Tocris).
    http://journals.lww.com/anesthesiology/fulltext/2003/03000/the_role_of_5_ht1a_..
  • New Imide 5-HT1A Receptor Ligands–Modification of Terminal ...
    geometry on 5-HT1A receptor affinity was analyzed in regard to model compounds NAN190 and MM199. Keywords: .... (base): δ (ppm) = 7.5-7.1 (m, 5H, arom), 7.1-6.7 (m, 4H, arom), 4.2-3.8 (m, 1H), 3.8 (s, 3H, OCH3),. 3.8-3.3 (m, 2H), 3,3-2.2 ...
    http://www.mdpi.com/1420-3049/9/3/170/pdf
  • Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination ...
    Abstract—The dual serotonin (5-HT) re-uptake inhibitor and 5-HT1A receptor agonist vilazodone was found to increase central ..... 5h (R = CO2Et). BOC. 4d a. b., c. Scheme 2. Reagents and conditions: (a) 5% Pd/C, H2, EtOH; (b) RCOCl, base, ...
    http://www.jain-resources.info/uploads/3/3/5/8/3358541/5ht1a_-_heinrich__.pdf
  • New Serotonin 5-HT1A Receptor Agonists with Neuroprotective Effect
    27 Oct 2011 ... The following compounds were synthesized according to described procedures: tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione (36),(55) tetrahydroimidazo[ 1,5-a]pyridine-1,3(2H,5H)-dione (37),(35) 1H-imidazo[1,5-c][1 ...
    http://pubs.acs.org/doi/abs/10.1021/jm2007886
  • Anxiety and the Serotonin Receptor
    The neural substrate for cybernetic dysfunction is unclear, although the observation that certain psychotherapeutic drugs may act, in part, through regulatory 5-HT1A autoreceptors is of interest. The 5-HT1A receptor was first described in 1981 ...
    http://www.acnp.org/g4/GN401000125/CH123.html
  • 5-HT1A and 5-HT1B receptors in the ventrolateral striatum ...
    5-HT1A receptor antagonist WAY-100635 maleate (WAY-. 100635; Sigma), the selective 5-HT1B receptor agonist. 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)- 5H- pyrrol[3,2-b]pyridine-5-one dihydrochloride (CP93129;. TOCRIS, Ellisville ...
    http://jos.dent.nihon-u.ac.jp/journal/50/4/387.pdf
  • Behavioral Profile of the 5HT1A Receptor
    Behavioral Profile of the 5HT1A Receptor. Antagonist (S)-UH-301 in Rodents and Monkeys. J.-L. MOREAUQ ..... selectivity for this recognition site over 5H'l',B_ SI- lT,C, and SHT2 receptor subtypes. When administered alone. (S)-UH-301 was ...
    http://perso.numericable.fr/griebguy/Pub009.pdf

Posted on 06/09/2011